Identification of single tumor cells in white matter distant from tumor center with IDH1 R132H antibody clone H09.
Infiltration zone of anaplastic astrocytoma with specific labelling of infiltrating glioma cells by antibody clone H09
Strong reaction of IDH1 R132H antibody clone H09 in tumor center of anaplastic oligoastrocytoma.
Double staining of GFAP (glial fibrillary acidic protein, red) and IDH1 R132H (brown) of oligodendroglioma infiltration zone demonstrating specific labelling of tumor cells but not of GFAP positive reactive astrocytes.
Cortex infiltrated by oligodendroglioma with specific labelling of tumor cells by IDH1 R132H antibody clone H09.
Strong reaction of IDH1 R132H antibody clone H09 with IDH1R132H mutated diffuse astrocytoma (left) but not with wild type tumor (right)
Immunohistochemistry of human IDH1 R132H in formalin-fixed paraffin-embedded brain tissue sections
Pictures courtesy of Prof. Dr. med. Andreas von Deimling, Department of Neuropathology, University Heidelberg / Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.